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NIOSH Testimony on Risk Estimates from the Cadmium Cohort Study by L. Stayner, February 7, 1992.

Authors
NIOSH
Source
NIOSH 1992 Feb:8 pages
Link
NIOSHTIC No.
00228292
Abstract
This testimony includes a table summarizing the risk estimates from fitting the multistage model to a specific cadmium (7440439) cohort study. The risk estimates from fitting the multistage model to the cadmium study were intermediate between estimates derived from fitting the Cox and Poisson regression models. NIOSH further notes that the risk estimates from the Cox and Poisson models are about 50% higher than the estimates in the risk assessment report submitted earlier by NIOSH. The lifetime risk was calculated over the entire life span rather than the median life span. Lung cancer rates were used rather than respiratory cancer rates. NIOSH assumed a five stage model for the analysis, as this is the number of stages generally observed in other multistage analyses of lung cancer. The model was fit by varying the stage affected by cadmium exposure and the model fit best when NIOSH assumed that cadmium affected the third stage.
Keywords
NIOSH-Author; NIOSH-Testimony; Stayner-L; Risk-analysis; Epidemiology; Cancer-rates; Mortality-data; Occupational-exposure;
CAS No.
7440-43-9;
Publication Date
19920207
Document Type
Testimony;
Fiscal Year
1992
NTIS Accession No.
PB95-267779
NTIS Price
A02
NIOSH Division
DSDTT;
Source Name
NIOSH, 8 pages, 4 references
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