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Silicosis and pulmonary cancer.

Authors
Goldsmith-DF; Schenker-M; Beaumont-JJ
Source
Department of Internal Medicine, Division of Occupational and Environmental Medicine-ITEH, University of California, Davis, California 1994 Apr; :1-5
Link
NIOSHTIC No.
00227286
Abstract
This report summarized the findings of a research project. In the determination of whether silicotics in California had excess mortality from pulmonary cancer for the period 1950 through 1984, the patients were found to have double the expected rate of mortality from lung cancer. Adjusting for partial smoking information, it was demonstrated that there was a residual risk directly related to silicosis. When examined by industry lung cancer risk indicated that construction had a standardized mortality ratio of 4.04, which could be confounded by asbestos (1332214) exposure. The risk of lung cancer was elevated for mining and metallurgy, but not for other industry groups. For the assessment of whether silicotics had increased mortality from gastric and hematopoietic malignancies, a follow up of the study could not confirm elevated mortality risks for either of those cancers. Lack of funding did not allow for the completion of the last three research aims, which involved the completion of the Registry of silicotics by the inclusion of claims from Southern California and from Federal Sources, validation of silicosis claims via a blind review of chest roentgenograms by two certified readers, and a comparison of smoking habits and work histories of lung cancer cases and matched controls.
Keywords
NIOSH-Grant; Pulmonary-system-disorders; Risk-factors; Risk-analysis; Cancer-rates; Lung-cancer; Respiratory-system-disorders; Asbestos-fibers; Construction-industry; Silicosis
Contact
Internal Medicine University of California Internal Medicine Davis, CA 95616
CAS No.
1332-21-4
Publication Date
19940425
Document Type
Final Grant Report
Funding Amount
300972
Funding Type
Grant
Fiscal Year
1994
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-02726
NIOSH Division
OEP
Priority Area
Pulmonary-system-disorders; Respiratory-system-disorders
Source Name
Department of Internal Medicine, Division of Occupational and Environmental Medicine-ITEH, University of California, Davis, California
State
CA
Performing Organization
University of California Davis, Davis, California
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