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Documentation for immediately dangerous to life or health concentrations (IDLHs).

Authors
Ludwig-HR; Cairelli-SG; Whalen-JJ
Source
Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 1994 May; :1-523
NIOSHTIC No.
00225285
Abstract
The sources of information and the criteria used to determine concentrations of various substances which have been deemed to be immediately dangerous to life and health (IDLHs) were reported. IDLHs were first established for 387 substances in the mid 1970s as part of the Standards Completion Program, which was a joint project of NIOSH and OSHA. The criteria and procedures used during the Standards Completion Program for establishing the IDLHs were considered, and the IDLHs were reviewed and revised. For each substance listed, information provided included any current exposure limits, the original IDLH, the basis for the original IDLH, acute toxicity data, human toxicity data, the revised IDLH, the basis for the revised IDLH, and references. The adequacy of each IDLH was determined based on a tiered approach. Human toxicity data were used preferentially, followed by acute animal inhalation toxicity data, and acute animal oral toxicity data. In the absence of relevant acute toxicity data, chronic toxicity data or toxicity data on an analogous chemical was used. Existing short term exposure guidelines and lower explosive limits were also considered.
Keywords
NIOSH-Author; Acute-toxicity; Inhalants; Comparative-toxicology; Respiratory-protection; Lung-irritants; Worker-health; Exposure-limits
Publication Date
19940501
Document Type
Other
Fiscal Year
1994
NTIS Accession No.
PB94-195047
NTIS Price
A23
NIOSH Division
DSDTT
Source Name
National Institute for Occupational Safety and Health
State
OH
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