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Respiratory symptoms, immunological responses, and aeroallergen concentrations at a sawmill.

Authors
Halpin-DMG; Graneek-BJ; Lacey-J; Nieuwenhuijsen-MJ; Williamson-PAM; Venables-KM; Taylor-AJ-Newman
Source
Occup Environ Med 1994 Mar; 51(3):165-172
NIOSHTIC No.
00219768
Abstract
An epidemiological, immunological, and environmental investigation of current and former workers at a sawmill and of a control population not occupationally exposed to wood or wood products was presented. About 3,300 cubic meters of timber was cut in the green mill at this facility each week. Conveyor belts were used to remove the sawdust from beneath the enclosed band saws. About 5% of the cut planks were treated with a fungicide in an automatic process with manual loading and unloading of the treatment tank. Of the 100 current workers, 95 completed questionnaires and performed spirometry. Blood samples were taken from 88 who also had skin prick tests performed. Seventeen exworkers were also studied. Exposure to wood dust at this mill was associated with an increased prevalence of symptoms related to nasal and conjunctival irritation and with a high prevalence of symptomatic bronchial hyperreactivity. Workers exposed to high concentrations of dust had more work related respiratory symptoms than those exposed to lower dust concentrations and cases of extrinsic allergic alveolitis occurred only in the more heavily exposed to wood dust with the higher concentrations of fungal spores. These workers had high concentrations of specific immunoglobulin-G against extracts of sawdust and Trichoderma-koningii.
Keywords
Immunological-tests; Allergic-reactions; Respiratory-system-disorders; Dust-exposure; Wood-dusts; Sawmill-workers; Lung-irritants; Fungi; Molds; Epidemiology; Skin-tests; Occupational-exposure
CODEN
OEMEEM
Publication Date
19940301
Document Type
Journal Article
Funding Amount
1055222
Funding Type
Cooperative Agreement
Fiscal Year
1994
NTIS Accession No.
NTIS Price
Identifying No.
Cooperative-Agreement-Number-U07-CCU-906162
Issue of Publication
3
ISSN
1351-0711
Source Name
Occupational and Environmental Medicine
State
CA
Performing Organization
University of California - Davis
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