Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Frequency selectivity in noise-damaged cochleas.

Authors
Davis-RI; Hamernik-RP; Ahroon-WA
Source
Audiology 1993 Mar; 32(2):110-131
NIOSHTIC No.
00215558
Abstract
The changes in tuning characteristics were investigated in chinchillas with specific patterns of noise induced cochlear sensory cell loss. A population of 363 noise exposed chinchillas was used to measure auditory threshold and masked threshold at six audiometric test frequencies. Surgically monaural chinchillas had been exposed to noise varying from very short duration, acute exposure at high intensities to lower level exposure for 5 days as part of other studies. From this group, 70 were chosen and separated into five groups based on the amount of permanent threshold shift and sensory cell losses the animals had incurred. A comparison was made of the tuning curve (TC) metrics to the mean preexposure TC metrics for each group and to the reference preexposure TC metrics obtained from the sample of 363 animals. The noise exposed chinchillas with no measurable permanent threshold shift (PTS) and not more than 3% cell loss in any given octave band demonstrated normal TC properties. For relatively low levels of PTS, TC slopes start to show statistically significant deviations from the norms. Results indicated that in populations with substantial PTS there are concomitant changes in TC metrics. Within regions of the noise damaged cochlea having normal populations of sensory cells, either normal or abnormal TC properties are noted.
Keywords
Noise-induced-hearing-loss; Laboratory-animals; Noise-exposure; Hearing-loss; Hearing-threshold; Sensory-thresholds; Cell-damage; Noise-frequencies; Audiometry; Auditory-feedback; Auditory-system; Animals; Animal-studies; Sampling; Sampling-methods
Contact
Communicative Disorders & Scis Research Foundation of Suny P O Box 9 Albany, NY 12201
CODEN
AUDLAK
Publication Date
19930301
Document Type
Journal Article
Funding Amount
2829511
Funding Type
Grant
Fiscal Year
1993
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-002317
Issue of Publication
2
ISSN
0020-6091
Source Name
Audiology
State
NY
Performing Organization
State University of New York at Buffalo, Buffalo, New York
TOP