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Mortality of Workers Employed at Organochlorine Pesticide Manufacturing Plants - An Update.

Authors
Brown-DP
Source
NIOSH 1991 Jul:27 pages
Link
NIOSHTIC No.
00211058
Abstract
A mortality study of workers at four organochlorine pesticide manufacturing factories was updated through 1987. The cohorts included all white male workers employed for at least 6 months before December 31, 1964 at the four factories. The workers had been exposed to the following organochlorine pesticides: chlordane (57749), heptachlor (76448), endrin (72208), aldrin (309002), dieldrin (60571), and dichlorodiphenyltrichloroethane (50293) (DDT). Workers at one factory had been exposed to the organobromine pesticide dibromochloropropane (96128). The total number of deaths for the period from 1976 through 1987 was 650. Mortality for all causes and all malignant neoplasms was lower that expected at each of the factories. Cerebrovascular disease mortality was elevated for three of the four factories. The most important result was the statistically significant increase in liver/biliary tract cancer among workers at the facility where aldrin and dieldrin were the primary organochlorine pesticides produced and the nonsignificant increase at the facility where DDT was manufactured.
Keywords
NIOSH-Author; Pesticide-industry; Agricultural-chemicals; Occupational-exposure; Epidemiology; Cancer-rates; Risk-factors; Organo-chlorine-compounds; Mortality-data;
CAS No.
57-74-9; 76-44-8; 72-20-8; 309-00-2; 60-57-1; 50-29-3; 96-12-8;
Publication Date
19910701
Document Type
Industry Wide;
Fiscal Year
1991
NTIS Accession No.
PB93-145738
NTIS Price
A03
NIOSH Division
DSHEFS;
Source Name
Industrywide Studies Branch, Division of Surveillance, Hazard Evaluations and Field Studies, NIOSH, Cincinnati, Ohio, 27 pages, 14 references
State
OH;
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