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HHE Report No. HETA-91-104-2229, Florida Hospital, Orlando, Florida.

Authors
Decker-J; Shults-RA
Source
NIOSH 1992 Jun:48 pages
NIOSHTIC No.
00210229
Abstract
In response to a request by hospital management to evaluate employee exposures to aerosolized ribavirin (36791045) (AR), an investigation was made at Florida Hospital (SIC-8062), Orlando, Florida. The hospital was an 801 bed medical center and teaching hospital. The investigation was conducted in the pediatric intensive care unit where AR was administered to infants and children. An aerosol containment device was used on most administrations of AR, and most health care workers used personal protective equipment as required by hospital policy. Urine samples (148) were collected from 44 health care workers and analyzed for ribavirin. Post shift urinary ribavirin concentrations equal to or above the limit of quantification of 0.01 micromole of ribavirin per liter of urine were found in 13 of 20 post shift urine samples from nurses and in three of 20 samples from respiratory therapists. Creatinine corrected post shift urinary ribavirin values ranged from less than mean of 0.017 micromole/gram. The mean post shift value for nurses was 0.030 micromole/gram while the mean for RTs was 0.004 micromole/gram.
Keywords
NIOSH-Author; NIOSH-Health-Hazard-Evaluation; NIOSH-Technical-Assistance-Report; HETA-91-104-2229; Hazard-Confirmed; Region-4; Health-care-personnel; Nursing; Urinalysis; Biological-monitoring; Occupational-exposure; Pharmaceuticals;
CAS No.
36791-04-5;
Publication Date
19920601
Document Type
Hazard Evaluation and Technical Assistance;
Fiscal Year
1992
NTIS Accession No.
PB93-119345
NTIS Price
A04
Identifying No.
HETA-91-104-2229
NIOSH Division
DSHEFS;
SIC Code
8062;
Source Name
Hazard Evaluations and Technical Assistance Branch, NIOSH, U.S. Department of Health and Human Services, Cincinnati, Ohio, Report No. HETA-91-104-2229, 48 pages, 46 references
State
FL; OH;
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