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The mutagenicity of electrocautery smoke.

Authors
Gatti-JE; Bryant-CJ; Noone-RB; Murphy-JB
Source
Plast Reconstr Surg 1992 May; 89(5):781-784
NIOSHTIC No.
00207009
Abstract
The mutagenicity of airborne smoke particles generated from the use of electrocautery knives during surgical procedures was studied. Air samples were collected on filters in two operating rooms during routine reduction mammoplasties involving extensive use of electrocautery knives. The samples were extracted and tested for mutagenic activity using the Salmonella microsomal microsuspension test with both (TA-98) and (TA-100) strains. After exposure to the smoke extracts, alteration of histidine dependence was seen in strain (TA-98). Samples extracted with methylene-chloride showed higher mutagenicity than those extracted using an XAD-2 column. The extracts had no effect on strain (TA-100) in mutagenicity tests. Some differences were seen in extracts obtained from different patients. No effects were seen after waiting 2 hours or more after surgery before extracting and testing the samples. The authors recommend the development of techniques to limit the exposure of operating room personnel to smoke from electrocautery knives.
Keywords
NIOSH-Author; Health-care-personnel; Aerosol-particles; Medical-equipment; Air-contamination; Air-samples; Occupational-exposure; Mutagens; Microbial-test-systems
CODEN
PRSUAS
Publication Date
19920501
Document Type
Journal Article
Fiscal Year
1992
NTIS Accession No.
NTIS Price
Issue of Publication
5
ISSN
0032-1052
NIOSH Division
DSHEFS
Source Name
Plastic and Reconstructive Surgery
State
OH; PA; NJ
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