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Immunological status and respiratory findings in furriers.

Authors
Zuskin-E; Kanceljak-B; Stilinovic-L; Schachter-EN; Kopjar-B
Source
Am J Ind Med 1992 Mar; 21(3):433-441
NIOSHTIC No.
00206092
Abstract
The relationship between respiratory dysfunction and immunological changes was examined in furriers exposed to different animal hairs. A group of 54 female employees of the fur coat industry was studied. The mean duration of employment was 11 years. All had typical skin reactions to histamine; none reacted to a buffer control solution. Seventeen percent of the workers reacted to house dust, but none to molds. Prevalences of immediate skin reaction decreased as follows: marten (10%), polar fox and lamb (7%), mink (5%), and Chinese lamb, domestic fox, and Chinese calf (2%). Exposure to some animal furs was associated with the development of precipitating antibodies. Four employees exhibited increased serum levels of immunoglobulin-E and complained of respiratory symptoms. Serum levels of other immunoglobulins were within normal limits. Reductions in ventilatory capacity over the work shift were recorded. Greater drops in respiratory parameters occurred in subjects with positive precipitins than in subjects with positive skin tests. The authors suggest that fur industry workers develop respiratory problems in association with specific indicators of atopy.
Keywords
NIOSH-Publication; NIOSH-Grant; Pulmonary-system-disorders; Respiratory-system-disorders; Immune-reaction; Allergic-reactions; Blood-analysis; Animal-products-workers; Occupational-exposure
Contact
Medicine Mount Sinai Medical Center One Gustave L Levy Place New York, N Y 10029
CODEN
AJIMD8
Publication Date
19920301
Document Type
Journal Article
Funding Amount
709316
Funding Type
Grant
Fiscal Year
1992
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-02593
Issue of Publication
3
ISSN
0271-3586
Priority Area
Pulmonary-system-disorders
Source Name
American Journal of Industrial Medicine
State
NY
Performing Organization
Mount Sinai School of Medicine, New York, New York
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