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A procedure for the analysis of pentamidine isethionate in air.

Authors
NIOSH
Source
Appl Occup Environ Hyg 1991 Nov; 6(11):920-921
NIOSHTIC No.
00203123
Abstract
Concerns regarding health care worker exposures to pentamidine (100334) prompted researchers at NIOSH to develop a sampling and analytical method for pentamidine in air. The method involves air sampling with a 37 millimeter polyvinyl-chloride membrane filter in an opaque cassette filter holder at 1 to 2 liters per minute, recovery of pentamidine-isothionate with 3 milliliter quantities of ethanol/water with 0.085% phosphoric-acid and 0.04% tetramethylammonium-chloride in an ultrasonic bath, and measurement by high performance liquid chromatography with fluorescence detection. The author notes that four studies are currently underway to evaluate health care workers' exposures to pentamidine using this procedure. These studies will evaluate exposure levels, assess control techniques, and evaluate health effects.
Keywords
NIOSH-Author; Pharmaceuticals; Health-care-personnel; Air-quality-monitoring; Air-sampling-techniques; Air-quality-control; Sampling-equipment; Analytical-methods
CODEN
AOEHE9
CAS No.
100-33-4
Publication Date
19911101
Document Type
Journal Article
Editors
Tharr-D
Fiscal Year
1992
NTIS Accession No.
NTIS Price
Issue of Publication
11
ISSN
1047-322X
Source Name
Applied Occupational and Environmental Hygiene
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