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Methodology for quantitative assessment of risks from chronic respiratory damage: lung function decline and associated mortality from coal dust.

Authors
Silver-K; Hattis-D
Source
Center for Technology, Policy and Industrial Development, Massachusetts Institute of Technology, Cambridge, Massachusetts, 1991 May; :1-62
Link
NIOSHTIC No.
00201452
Abstract
The 1 second forced expiratory volume (FEV1) was used as a predictor of excess general mortality and as an indicator of progressive deterioration to respiratory impairment as a result of exposure to coal dust. Data on 1,362 coal miners who had never smoked were used. The adequacy of nine different linear regression models for representing the effects of coal dust, age and height on FEV1 were compared. The data regarding the effects of working lifetime exposures to concentrations of coal dust up to and including the current mandated maximum level of United States mines were summarized. It was noted that the mortality and morbidity effects projected were appreciable in relation to those that have motivated previous efforts toward additional control of other occupational health hazards. Relatively large amounts of interindividual variability were noted in susceptibility for the processes leading to chronic bronchitis. Moderate amounts of interindividual variability in susceptibility to the production of the radiographic changes that define various grades of coal workers' pneumoconiosis were noted. Inconclusive evidence was gained for interindividual variability in the chronic cumulative reduction of FEV1 in response to coal dust. The authors conclude that significant additional public health benefits are likely to result from reducing exposures to below 2mg/m3.
Keywords
Coal-miners; Mining-industry; Mineral-dusts; Respiratory-system-disorders; Pulmonary-function-tests; Mortality-data; Epidemiology; Pulmonary-function;
Publication Date
19910501
Document Type
Cooperative Agreement; Interagency Agreement
Funding Type
Cooperative Agreement; Interagency Agreement
Fiscal Year
1991
NTIS Accession No.
PB92-115658
NTIS Price
A05
Identifying No.
IA-U6O-CCU-100929
Priority Area
Asthma and Chronic Obstructive Pulmonary Disease; Disease and Injury; Respiratory-system-disorders;
Source Name
Center for Technology, Policy and Industrial Development, Massachusetts Institute of Technology, Cambridge, Massachusetts, 62 pages, 32 references
State
MA
Performing Organization
Massachusetts Institute of Technology, Cambridge, Massachusetts
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