Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Urolithiasis in Tennessee: an occupational window into a regional problem.

Authors
Thun-MJ; Schober-S
Source
Am J Publ Health 1991 May; 81(5):587-591
NIOSHTIC No.
00200455
Abstract
This study began as an investigation of reported urinary tract disorders among uranium workers in eastern Tennessee. The facility processed depleted and natural uranium (7440611) and thorium (7440291) from 1957 through 1970, and enriched uranium after 1970. The target population included highly exposed active, retired and disabled production workers with 20 years employment before 1986; a low exposure group of senior office and laboratory workers; minimally exposed guards, aged 40 to 65, exposed recently at the facility; and unexposed dairy workers from a nearby town. The principal result was an increased risk of stones among males in eastern Tennessee. At highest risk were persons with a positive family history whose urine was supersaturated with calcium-oxalate. Biochemical factors influencing the risk of lithogenesis were hypercalciuria, hyperoxaluria, and low urine volume. The occurrence of stones among uranium workers bore no relation to the intensity or duration of occupational exposure. Stones were slightly less common in workers with direct exposure to uranium and thorium than in unexposed workers. Stone occurrence was similar in the uranium and dairy workers. The authors conclude that the risk of stones was regional rather than occupational.
Keywords
NIOSH-Author; Urinalysis; Uranium-compounds; Uranium-ore; Epidemiology; Urogenital-system-disorders; Urine-chemistry; Kidney-disorders; Nephrological-disorders; Kidney-function; Humans
CODEN
AJHEAA
CAS No.
7440-61-1; 7440-29-1
Publication Date
19910501
Document Type
Journal Article
Fiscal Year
1991
NTIS Accession No.
NTIS Price
Issue of Publication
5
ISSN
0090-0036
Source Name
American Journal of Public Health
State
TN
TOP