Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Testicular cancer, dimethylformamide, and leather tanneries.

Authors
Calvert-GM; Fajen-JM; Hills-BW; Halperin-WE
Source
Lancet 1990 Nov; 336(8725):1253-1254
NIOSHTIC No.
00199977
Abstract
A testicular cancer screening program was offered to all known former and current male finishing department workers employed at a tannery from 1975 to 1989, to investigate a report of a cluster of three men with testicular cancer who worked in the finishing department of the tannery. Testicular cancer was not found in any of the 51 workers screened. An industrial hygiene evaluation of the finishing department was done in April, 1989. The results of air samples indicated that there were no detectable levels of dimethylformamide (68122) (DMF), trace metals, nitrosamines, benzidine (92875), or aldehydes. Personal air samples had a mean concentration of 0.65mg/m3 for 2-ethoxyethanol (110805), 0.23 mg/m3 for 2-ethoxyethylacetate (111159), 4.2mg/m3 for 2-butoxyethanol (111762), and 4.0mg/m3 for diisobutyl-ketone (108838). One participant reported a history of alcohol intolerance. This worker frequently had to reach into drums of DMF containing dyes and denied ever using personal protective equipment such as gloves or a respirator. Two individuals had liver injury and both men had conditions apart from DMF exposure that could have been responsible for this problem. According to the authors, results confirm the excess of testicular cancer at the tannery.
Keywords
NIOSH-Author; Tanning-industry; Liver-damage; Reproductive-system-disorders; Reproductive-hazards; Amides; Leather-industry; Leather-workers; Occupational-exposure
CODEN
LANCAO
CAS No.
68-12-2; 92-87-5; 110-80-5; 111-15-9; 111-76-2; 108-83-8
Publication Date
19901117
Document Type
Journal Article
Fiscal Year
1991
NTIS Accession No.
NTIS Price
Issue of Publication
8725
ISSN
0140-6736
NIOSH Division
DSHEFS
Priority Area
Reproductive-system-disorders
Source Name
Lancet
State
OH
TOP