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Health hazard evaluation report: HETA-89-116-2094, Westinghouse Electric Corporation, Bloomington, Indiana.

Authors
Sinks-T; Smith-AB; Rinsky-R; Watkins-K; Shults-R; Steele-G
Source
NIOSH 1991 Jan; :1-28
NIOSHTIC No.
00199122
Abstract
NIOSH conducted a retrospective cohort study of workers manufacturing electrical capacitors with known exposure to polychlorinated biphenyls (1336363) (PCBs) in an effort to further evaluate the carcinogenicity of PCBs. The study cohort manufactured electric capacitors in the midwest United States beginning in 1957. PCBs were used as a dielectric fluid until late in 1977 when they were replaced with isopropyl-biphenyl (25640782). Aroclor-1242 (53469219) was used through 1970 and Aroclor-1016 (12674112) was used afterwards. Included in the analysis were 3588 men and women employed for at least one day between January 1, 1957 and March 31, 1977. The results provided some evidence for an association between PCB exposure in an occupational environment and mortality from malignant melanoma. There was an increased incidence of brain cancer among workers who had more than twice the estimated cumulative PCB dose than the comparison group. The authors conclude that this brain cancer observation suggests that this outcome be carefully observed in further followup of this cohort.
Keywords
NIOSH-Author; NIOSH-Health-Hazard-Evaluation; NIOSH-Technical-Assistance-Report; HETA-89-116-2094; Hazard-Confirmed; Region-5; Polychlorinated-biphenyls; Brain-damage; Central-nervous-system; Mortality-data; Occupational-exposure; Epidemiology; Chlorinated-hydrocarbons; Author Keywords: Electrical industrial apparatus; polychlorinated biphenyl; PCB; Aroclor; malignant melanoma; brain cancer; mortality
CAS No.
1336-36-3; 25640-78-2; 53469-21-9; 12674-11-2
Publication Date
19910101
Document Type
Hazard Evaluation and Technical Assistance; Field Studies
Fiscal Year
1991
NTIS Accession No.
PB91-212613
NTIS Price
A03
Identifying No.
HETA-89-116-2094
NIOSH Division
DSHEFS
SIC Code
3629
Source Name
Hazard Evaluations and Technical Assistance Branch, NIOSH, U.S. Department of Health and Human Services, Cincinnati, Ohio, Report No. HETA-89-116-2094, 28 pages, 37 references
State
IN; OH
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