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Muscularization of Pulmonary Arteries in Coal Workers Pneumoconiosis.

Authors
Hu-N; Vallyathan-V; Green-FH; Weber-KC
Source
NIOSH 1990 Nov:1526-1534
NIOSHTIC No.
00198721
Abstract
An investigation was conducted to examine the differences between the etiology and pathophysiology of two types of muscular hypertrophy in the terminal pulmonary arterial trees in coal worker's pneumoconiosis (CWP), namely longitudinally oriented and circularly oriented smooth muscle hypertrophy. For this investigation 72 autopsies without heart valvular or severe coronary lesions and without hypertensive left ventricular hypertrophy were drawn from a series of 120 unselected consecutive autopsies. The results indicated that circular smooth muscle hypertrophy in the medial wall of pulmonary arterioles demonstrated a high correlation with the incidence of right ventricular hypertrophy (RVH) in 57 CWP cases and 15 referent cases from the Appalachian region. Intimal longitudinal muscle hypertrophy, or medical circular muscle hypertrophy in small pulmonary arteries did not reveal such correlation with RVH.
Keywords
Respiratory-system-disorders; Lung-disease; Cardiovascular-system-disorders; Coal-workers-pneumoconiosis; Coal-dust; Dust-exposure; Postmortem-examination;
Publication Date
19901101
Document Type
Conference/Symposia Proceedings;
Fiscal Year
1991
NTIS Accession No.
NTIS Price
Identifying No.
(NIOSH) 90-108
Priority Area
Asthma and Chronic Obstructive Pulmonary Disease; Disease and Injury; Respiratory-system-disorders;
Source Name
Proceedings of the VIIth International Pneumoconioses Conference
State
PA;
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