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Inhaled Corticosteroids in the Treatment of Occupational Respiratory Diseases (O.R.D.).

Authors
Rosal Goncalves-J; Correia-I; Raymundo-E; Araujo-A; Costa-MF
Source
NIOSH 1990 Sep:443-451
NIOSHTIC No.
00198442
Abstract
An investigation was conducted to evaluate the effectiveness of the inhaled corticosteroids in the treatment of occupational respiratory diseases. The investigation involved 15 patients aged 28 to 66 years. Nine had a consistent occupational history of exposition to mineral dusts (five to silica (14808607), three to iron (7439896), and one to asbestos (1332214)), and six to organic dust (three to cork dust and three to pigeon droppings). Prior to treatment all patients had complaints of exertion dyspnea, 93% experienced cough, 53% expectoration, and 46% wheezing. All patients were treated with Budesonide 4x200 micrograms twice a day, via a 750 milliliter spacer. After 3 months of treatment the clinical evaluation stated an improvement in 80% of the patients. The only side effects were two cases of mild sore throats and one of hoarseness. The results provided some evidence of the effectiveness of the proposed treatment, mainly in the interstitial occupational respiratory diseases.
Keywords
Epidemiology; Silica-dusts; Dust-inhalation; Dust-exposure; Respiratory-system-disorders; Pulmonary-function-tests; Medical-treatment; Asbestos-workers; Pigeon-breeders-disease; Plant-dusts;
CAS No.
14808-60-7; 7439-89-6; 1332-21-4;
Publication Date
19900901
Document Type
Conference/Symposia Proceedings;
Fiscal Year
1990
NTIS Accession No.
NTIS Price
Identifying No.
(NIOSH) 90-108
Priority Area
Asthma and Chronic Obstructive Pulmonary Disease; Disease and Injury; Respiratory-system-disorders;
Source Name
Proceedings of the VIIth International Pneumoconioses Conference
State
PA;
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