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Lung disease in Chinese textile workers.

Authors
Christiani-DC; Wegman-DH; Ye-T; Lu-P
Source
Occupational Health Program, Harvard School of Public Health, Boston, Massachusetts 1990 Nov; :1-31
Link
NIOSHTIC No.
00197966
Abstract
Studies were conducted to determine the 5 year incidence and remission of byssinosis and nonspecific respiratory symptoms of cotton textile workers; to determine the rate of annual decline in pulmonary function; to explore the relative contributions of cotton dust and airborne gram negative endotoxin exposure in development and progression of respiratory symptoms and pulmonary function change; and to explore the persistence of cross shift drops in forced expiratory volume in 1 second (FEV1) over a 5 year period and the association of cross shift change in FEV1 at baseline survey and subsequent development of respiratory symptoms and accelerated loss of FEV1. This 5 year longitudinal study involved 447 cotton textile and 465 silk textile workers in Shanghai, China. Cotton textile workers lost FEV1 at a greater rate than silk textile workers. This accelerated loss in cotton workers occurred in both smokers and nonsmokers. A significant effect of cotton dust exposure was noted. A cross shift change in FEV1 at the time of first survey was strongly predictive of subsequent 5 year loss of FEV1. Exposure to endotoxin was stronger than chest tightness in predicting dyspnea among male cotton workers. There was no detectable dose response relationship for dust or endotoxin in predicting 5 year loss in FEV1. The acute responses to cotton dust seem to predict long term lung function loss.
Keywords
NIOSH-Grant; Pulmonary-system-disorders; Textiles-industry; Textile-workers; Pulmonary-function-tests; Cotton-industry; Cotton-mill-workers
Contact
Environmental Sci & Physiology Harvard School of Public Hlth 665 Huntington Ave Boston, MA 02115
Publication Date
19901115
Document Type
Final Grant Report
Funding Amount
1348724
Funding Type
Grant
Fiscal Year
1991
NTIS Accession No.
PB91-184481
NTIS Price
A04
Identifying No.
Grant-Number-R01-OH-002421
NIOSH Division
OEP
Priority Area
Pulmonary-system-disorders
Source Name
Occupational Health Program, Harvard School of Public Health, Boston, Massachusetts
State
MA
Performing Organization
Harvard University
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