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Validation of a Neurobehavioral Test System.

Authors
Letz-R
Source
Division of Environmental and Occupational Medicine, Mount Sinai School of Medicine, New York, New York 1990 Mar:35 pages
Link
NIOSHTIC No.
00197939
Abstract
This study attempted to validate tests from the computerized Neurobehavioral Evaluation System (NES) for use in field investigations where repeated testing of the same subjects is required. Personal samples of styrene (100425) in the breathing zone air and post shift urinary mandelic-acid (90642) were collected for 116 workers in six fiberglass boat building companies located in New England. The average exposure to styrene was 4.6 years with an 8 hour time weighted average styrene exposure of 29.9 parts per million (ppm) and urinary mandelic-acid averaging 490 milligrams/gram creatinine. A statistically significant relationship was found between post shift performance on the Symbol/Digit test and both acute styrene exposure and mandelic-acid concentration. Other analyses comparing workers exposed to less than 50ppm and greater than 50ppm styrene also showed a significant difference in Symbol/Digit performance. All three NES tests showed test/retest correlation coefficients above 0.80, and ease of use for collection of neurobehavioral data under field conditions was demonstrated.
Keywords
NIOSH-Grant; Neurotoxic-effects; Nervous-system-disorders; Urinalysis; Fiberglass-industry; Boat-manufacturing-industry;
Contact
Community Medicine Mount Sinai School of Medicine One Gustave L Levy Place New York, N Y 10029
CAS No.
100-42-5; 90-64-2;
Publication Date
19900309
Document Type
Final Grant Report;
Funding Amount
205288.00
Funding Type
Grant;
Fiscal Year
1990
NTIS Accession No.
PB91-184572
NTIS Price
A04
Identifying No.
Grant-Number-R01-OH-02384
NIOSH Division
OEP
Priority Area
Neurotoxic Disorders; Neurotoxic-effects;
Source Name
Division of Environmental and Occupational Medicine, Mount Sinai School of Medicine, New York, New York
State
NY;
Performing Organization
Mount Sinai School of Medicine, New York, New York
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