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Risks of Pathologists Exposed to Formaldehyde.

Authors
Matanoski-GM
Source
School of Hygiene and Public Health, Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland 1989 Aug:32 pages
Link
NIOSHTIC No.
00197319
Abstract
A study was conducted to determine if pathologists with exposure to formaldehyde (50000) demonstrate an excess risk of cancer, particularly cancers of the nasopharyngeal and pharyngeal areas. A population of 6411 physicians with occupational formaldehyde exposure participated in the study. The occurrence of these types of cancers was 4.7 times higher in these persons than in a comparable sized group of psychiatrists, but even so it is difficult to determine the importance of this increased risk as being directly tied to formaldehyde exposure. Pathologists and other members of the study group were exposed to other chemicals and infectious agents as well as formaldehyde. There was an apparent excess of mortality from pancreatic cancer and brain cancers as well as leukemia. According to the author, it is difficult to see how a large dose of the agent could be absorbed and reach these areas of the body as formaldehyde is such an irritating substance.
Keywords
NIOSH-Grant; Cancer; Cancer-rates; Epidemiology; Laboratory-workers; Risk-factors; Nasal-cancer; Nasal-cavity; Occupational-exposure;
Contact
Epidemiology Johns Hopkins University 615 North Wolfe Street Baltimore, MD 21205
CAS No.
50-00-0;
Publication Date
19890809
Document Type
Final Grant Report;
Funding Amount
267067.00
Funding Type
Grant;
Fiscal Year
1989
NTIS Accession No.
PB91-173682
NTIS Price
A04
Identifying No.
Grant-Number-R01-OH-01511
NIOSH Division
OEP
Source Name
School of Hygiene and Public Health, Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland
State
MD;
Performing Organization
Johns Hopkins University, Baltimore, Maryland
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