A strategy was developed for the prevention of occupationally induced cancer in workers. In most cases, occupationally induced cancer occurs decades after the initial exposures that cause the disease process to begin. It was over 200 years ago that it was first recognized that chemical agents in the workplace were responsible for illnesses among workers. Current estimates of the scope of the problem vary widely. Data from 1972 estimate that 110,000 workers are potentially exposed to the 21 chemicals currently regulated as carcinogens by OSHA. A continuum of techniques is offered which potentially are useful for preventing occupational cancer. The identification and evaluation of carcinogens is one of the steps to be taken immediately. This identification will be followed by the setting of standards to prevent exposure to the identified substance. Elimination of the substance through substitution of a less hazardous material is one control method which must be examined carefully. Current and future control technologies are considered along with the usefulness of personal protective devices, environmental monitoring, biologic monitoring, medical screening, health promotion, therapeutic health care and rehabilitation, surveillance for disease, compliance activities, education of workers and managers, and the use of free market forces for prevention.