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Vibrotactile threshold measurement for detecting neurotoxicity: reliability and determination of age- and height-standardized normative values.

Authors
Gerr-F; Hershman-D; Letz-R
Source
Arch Environ Health 1990 May; 45(3):148-154
NIOSHTIC No.
00195285
Abstract
The results of two investigations of vibrotactile threshold test performance were presented. In the first investigation, the test/retest reliability and time efficiency of two methods of threshold generation were determined in 22 subjects with diabetes drawn from a hospital based clinic. Specifically, a forced choice method was compared to a method of limits (MOL) procedure. The second investigation was performed to determine major effect modifiers of vibrotactile thresholds measured with the MOL procedure and to provide provisional normative values. The MOL proved to be a reliable and time efficient procedure during its test on 131 blue collar workers who were 29 to 76 years of age. Age and height were noted to significantly effect modifiers and had to be controlled for when vibrotactile thresholds were measured for either clinical or epidemiologic purposes. Other sources of variability have to be identified. The authors state that specific attention must be given to the effects of calluses, local trauma, medical illness, substance use and other parameters. Additional validation must include comparison of these measurements to conventional clinical tests, including physical examination and electroneurography. Finally, the utility of these measurements as early markers of disease must be evaluated in prospective investigations.
Keywords
NIOSH-Publication; NIOSH-Grant; Nervous-system-disorders; Medical-screening; Age-factors; Neurological-reactions; Neuropathology; Ergonomics; Biomechanics
Contact
Community Medicine Mount Sinai School of Medicine One Gustave L Levy Place New York, N Y 10029
CODEN
AEHLAU
Publication Date
19900501
Document Type
Journal Article
Funding Amount
32400
Funding Type
Grant
Fiscal Year
1990
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-K01-OH-000064
Issue of Publication
3
ISSN
0003-9896
Source Name
Archives of Environmental Health
State
NY
Performing Organization
Mount Sinai School of Medicine, New York, New York
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