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The effects of inorganic lead on behavioral and neurologic function. Final report.

Authors
Repko-JD; Corum-CR; Jones-PD; Garcia-LS Jr.
Source
NIOSH 1978 Jan; :1-102
Link
NIOSHTIC No.
00194416
Abstract
Subjects in this study of the effects of lead (7439921) exposure on behavioral and neurologic function were employed in two regions of the United States. Of the 140 workers sampled, 85 workers were exposed to lead in the job and 55 served as comparisons. Each worker who volunteered for the study was subjected to 53 behavioral measures of sensory and motor functioning, six measures of nerve conduction velocity, five indices of inorganic lead absorption, a clinical electromyogram, and a clinical neurological examination. Demographic data were also collected from each participant. The exposed workers were employed in the storage battery manufacturing industry. Based on the data obtained in this study and others, the adverse effects of occupational exposure to inorganic lead (7439921) on certain functional capacities was demonstrated. Quantifiable behavioral and neurological effects were noted at levels below the accepted biologic guideline of 80 micrograms of lead per 100 milliliters of blood. Deficits in the peripheral nerves, in visual reaction time, as well as deficits in auditory functioning were demonstrated. According to the authors, questions concerning the progression of these effects and their reversibility in individual workers must be addressed.
Keywords
NIOSH-Contract; Contract-210-75-0054; Nervous-system-disorders; Neuropathology; Lead-poisoning; Behavioral-disorders; Battery-manufacturing-industry; Heavy-metals; Toxic-effects
CAS No.
7439-92-1; 7439-92-1
Publication Date
19780101
Document Type
Numbered Publication
Funding Type
Contract
Fiscal Year
1978
NTIS Accession No.
PB91-108126
NTIS Price
A07
Identifying No.
(NIOSH) 78-128; Contract-210-75-0054
NIOSH Division
DBBS
Source Name
National Institute for Occupational Safety and Health
State
OH
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