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Carbon monoxide and human functions.

Authors
Beard-RR; Grandstaff-NW
Source
Department of Community and Preventive Medicine, Stanford University, Stanford, California 1972 Jun; :1-35
Link
NIOSHTIC No.
00190686
Abstract
The effects of low concentrations of carbon-monoxide (630080) (CO) on several aspects of cerebral functions in man were examined. These functions included perception, discrimination, memory and complex cognitive processes. The study participants included healthy young male and female Stanford students between ages 18 and 25 years. Each subject was exposed to CO in a chamber from which the air was continuously sampled. CO concentrations were 50, 175, or 250 parts per million. Each daily test session consisted of four rounds of 40 minutes each, divided into a 25 or 20 minute test period and a 15 or 20 minute rest period. Vigilance was significantly reduced and the performance of a given task involving estimation of time and motion together was also compromised. Only marginal impairment was noted in a complex problem solving test. No consistency or reliability was discerned in the effects on spatial perception, digit span, or arithmetic performances.
Keywords
NIOSH-Grant; Neurotoxic-effects; Task-performance; Work-capability; Toxic-gases; Humans; Toxic-effects
Contact
Preventive Medicine Stanford University Sch of Med Stanford, Calif 94305
CAS No.
630-08-0
Publication Date
19720607
Document Type
Final Grant Report
Funding Amount
285128
Funding Type
Grant
Fiscal Year
1972
NTIS Accession No.
PB90-129883
NTIS Price
A04
Identifying No.
Grant-Number-R01-OH-00327
NIOSH Division
OEP
Priority Area
Neurotoxic Disorders
Source Name
Department of Community and Preventive Medicine, Stanford University, Stanford, California
State
CA
Performing Organization
Stanford University, Stanford, California
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