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HETA Report No. HETA-83-422-L1965, Department of Energy, Martin Marietta Energy Systems, Inc., Health Evaluation of Y-12 Workers Formerly Exposed to Mercury.

Authors
NIOSH
Source
NIOSH 1987 May:235 pages
Link
NIOSHTIC No.
00190275
Abstract
The possibility that a relationship existed between occupational mercury (7439976) exposure at the Y-12 facility, Department of Energy, Martin Marietta Energy Systems, Inc., and persistent health effects. The cohort of workers studied included those whose work experience lasted at least 4 months at the Y-12 facility between 1953 and 1966. Only two significant differences were noted after the data was analyzed between mercury exposed and comparison groups: decreased proximal strength and sensory median amplitude. These differences were small in magnitude and lacking in clinical meaning. In the dose/response analyses, 11 of the almost 60 clinical, quantitative and electrodiagnostic variables were weakly and significantly related to either integrated or peak urine mercury exposures. Each of the 11 demonstrated abnormalities in the mercury exposed group. There findings, however, were not sufficient to conclude that prior mercury exposure was associated with a chronic sensorimotor peripheral polyneuropathy. Subjects with urine mercury levels above 0.6 milligrams/liter demonstrated slightly poorer performance than the remaining subjects including decreased strength, decreased coordination, increased tremor, decreased sensation, and increased prevalence of Babinski and snout reflexes which were consistent with small, subclinical central and peripheral nervous system adverse effects. For the vast majority of subjects there was no evidence of a definite tremor, no adverse reproductive outcome, and no evidence of a dose response relationship between any cognitive measures and exposure measures.
Keywords
NIOSH-Author; NIOSH-Health-Hazard-Evaluation; NIOSH-Technical-Assistance-Report; HETA-83-422-L1965; Region-4; Hazards-Unconfirmed; Mercury-poisoning; Nervous-system-disorders; Neuropathology; Reproductive-hazards; Renal-toxicity; Psychomotor-disorders; Toxic-effects;
CAS No.
7439-97-6;
Publication Date
19870501
Document Type
Hazard Evaluation and Technical Assistance;
Fiscal Year
1987
NTIS Accession No.
PB90-119918
NTIS Price
A12
Identifying No.
HETA-83-422-L1965
NIOSH Division
DSHEFS;
Source Name
Hazard Evaluations and Technical Assistance Branch, NIOSH, Cincinnati, Ohio, Report No. HETA-83-422-L1965, 235 pages, 57 references
State
OH;
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