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Review and Evaluation of Recent Scientific Literature Relevant to an Occupational Standard for Ethylene Dibromide.

Authors
Anonymous
Source
Syracuse Research Corporation, Center for Chemical Hazard Assessment, Syracuse, New York 1979 Nov:66 pages
Link
NIOSHTIC No.
00188268
Abstract
This report served as a critical review and evaluation of recent literature concerning hazards associated with exposure to ethylene- dibromide (106934). Workers exposed to ethylene-dibromide may experience severe acute respiratory damage, central nervous system depression, and severe vomiting on inhalation of the vapors. Skin contact can cause erythema, blistering, and ulceration. A recommended ceiling level for occupational exposures has been set by NIOSH at 1mg/m3. NIOSH has identified the following areas as needing future research: epidemiological surveys, liver and kidney function tests, and biological monitoring among exposed workers. It was also recommended that animal studies be conducted with regard to possible carcinogenic, mutagenic, and teratogenic effects. Other specific areas covered in the review included the results of animals studies already conducted in the areas of carcinogenicity, mutagenicity, reproductive effects, developmental effects, hepatic effects, metabolic studies, synergistic effects, general toxicity, work practices, engineering controls, sampling and analytical methods.
Keywords
NIOSH-Contract; Contract-210-78-0009; Fumigants; Pulmonary-system-disorders; Central-nervous-system-disorders; Irritants; Laboratory-animals; Personal-protective-equipment; Inhalants; Skin-exposure; Occupational-exposure; Toxic-effects;
CAS No.
106-93-4;
Publication Date
19791101
Funding Type
Contract;
Fiscal Year
1980
NTIS Accession No.
PB89-215792
NTIS Price
A05
Identifying No.
Contract-210-78-0009
Priority Area
Asthma and Chronic Obstructive Pulmonary Disease; Disease and Injury; Pulmonary-system-disorders; Control Technology and Personal Protective Equipment; Research Tools and Approaches;
Source Name
Syracuse Research Corporation, Center for Chemical Hazard Assessment, Syracuse, New York
State
NY;
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