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Special occupational hazard review for DDT.

Authors
NIOSH
Source
NIOSH 1978 Sep; :1-214
NIOSHTIC No.
00184343
Abstract
This Hazard Review examined problems associated with the use and manufacture of DDT (50293). The use of DDT has been restricted in the United States to specific applications by the Department of Agriculture and the Public Health Department, and for controlling body lice. In other countries, DDT was still used widely in agriculture and for vector control. Studies indicated that the estimated oral toxicity for humans was 250mg/kg. Animal studies suggested that chronic effects may occur in humans exposed for long periods of time, possibly even the production of cancer. DDT has produced an increased incidence of tumors in mice, mostly involving the liver, but also involving the lungs and lymphatic system. Studies with mice showed increased tumor incidence at dietary level as low as 2 to 10 parts per million. NIOSH recommends that DDT be controlled and handled in the workplace as a suspected carcinogen. Exposure should be kept to the minimum. Airborne levels of DDT should not exceed 0.5mg/m3. Workers should avoid skin contact as the pesticide can be absorbed through the skin. This absorption is enhanced in the presence of organic solvents.
Keywords
NIOSH-Criteria-Document; Organo-chlorine-compounds; Pesticides; Agricultural-chemicals; Chlorinated-hydrocarbon-pesticides; Toxic-effects; Carcinogens; Occupational-exposure
CAS No.
50-29-3
Publication Date
19780901
Document Type
Numbered Publication; Criteria Document
Fiscal Year
1978
NTIS Accession No.
PB81-226656
NTIS Price
A11
Identifying No.
(NIOSH) 78-200
NIOSH Division
DCDSD
Source Name
National Institute for Occupational Safety and Health
State
OH
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