Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Criteria for a recommended standard... occupational exposure to ethylene dichloride (1,2-dichloroethane).

Authors
NIOSH
Source
NIOSH 1976 Mar; :1-165
NIOSHTIC No.
00184103
Abstract
NIOSH recommends in this document that worker exposure to ethylene- dichloride (107062) be controlled so that no worker is exposed in excess of 5 parts per million (ppm) determined as a time weighted average for up to a 10 hour workday, 40 hour workweek, or to peak concentrations above 15ppm as determined by a 15 minute sample. Nursing mothers should not work with ethylene-dichloride. Medical provisions include the offering of comprehensive preplacement and annual medical examinations, proper medical management for exposed workers, and the keeping of medical records. Labeling requirements are defined. Personal protective equipment and clothing for workers includes respiratory protection, gloves, boots, overshoes, and bib type aprons, and eye protection. Employees shall be informed of the hazards from ethylene-dichloride exposure. Good work practices shall be maintained and emergency procedures and confined space entry procedures fully outlined. Documented effects on humans from exposure included death as a result of ingestion, preceded by dizziness, nausea, vomiting, and unconsciousness. Autopsies revealed hyperemia and hemorrhagic lesions of most organs. Inhalation of vapors has also resulted in death with similar pathological findings. Repeated and chronic occupational exposures have resulted in anorexia, nausea, vomiting, epigastric pain, irritation of the mucous membranes, and liver and kidney dysfunction. A delay in the onset of symptoms following inhalation exposures may signify the metabolism of the parent compound to more toxic metabolites. Ethylene-dichloride has been shown to be weakly mutagenic.
Keywords
NIOSH-Criteria-Document; Chemical-manufacturing-industry; Agricultural-chemicals; Insecticides; Chlorinated-ethylenes; Chlorinated-hydrocarbons; Toxic-effects; Mutagens
CAS No.
107-06-2
Publication Date
19760301
Document Type
Numbered Publication; Criteria Document
Fiscal Year
1976
NTIS Accession No.
PB85-178275
NTIS Price
A09
Identifying No.
(NIOSH) 76-139
Source Name
National Institute for Occupational Safety and Health
State
OH
TOP