Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Health hazards of tertiary amine catalysts.

Authors
Albrecht-WN; Stephenson-RL
Source
Scand J Work, Environ & Health 1988 Aug; 14(4):209-219
NIOSHTIC No.
00182851
Abstract
The health hazards of tertiary amine catalysts used in foundry and polyurethane foam manufacturing processes were reviewed and discussed. In foundries, tertiary amine catalysts have been used in the core making processes to increase the rate of reaction between phenolic resins and isocyanates. In polyurethane foam making processes, tertiary amine catalysts have been used to control the rate of reaction of polyfunctional isocyanates and hydroxyl containing polymers. Chemical parameters discussed included the basic and nucleophilic properties of the amines and their aqueous and lipid solubilities. General toxicological effects included corrosive action on the skin and mucous membranes and systemic complaints including headache, nausea, faintness, anxiety, tachycardia, itching, erythema, urticaria, and edema. Specific visual effects included corneal edema, misty vision, halo vision, and blue or grey vision with haziness. Experimental investigations have been conducted on mechanisms underlying the visual and systemic effects of tertiary amine exposure, included mydriasis and cylcoplegia due to effects on the innervation of the sphincter muscle of the iris, edema and rupture of the corneal epithelium, blockade of parasympathetic and sympathetic ganglia, and histamine release.
Keywords
NIOSH-Author; Clinical-symptoms; Plastics-industry; Eye-disorders; Occupational-exposure; Foundry-workers; Synthetic-materials
CODEN
SWEHDO
Publication Date
19880801
Document Type
Journal Article
Fiscal Year
1988
NTIS Accession No.
NTIS Price
Issue of Publication
4
ISSN
0355-3140
Source Name
Scandinavian Journal of Work, Environment and Health
TOP