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Elemental mercury exposure: correlation of urine mercury indices with ulnar nerve conduction studies.

Authors
Levine-SP; Cavender-GD; Langolf-GD; Albers-JW
Source
University of Michigan Medical Center, Department of Physical Medicine and Rehabilitation, Ann Arbor, Michigan, 1982 Jan; :1-16
Link
NIOSHTIC No.
00181011
Abstract
An electrophysiological evaluation was made of the ulnar nerve in 18 men who were exposed to elemental mercury (7439976) vapor in the course of their jobs at a mercury cell chlorine plant. The men averaged 31 years of age, ranging from 19 to 56. Urinary mercury levels were determined routinely at this facility and were thus available for 3 years prior to the evaluation of the ulnar nerve. Conventional techniques were used to measure compound muscle action potential and sensory nerve action potential (SNAP) negative peak amplitudes, motor and sensory distal latency, and maximum motor conduction velocity. Abnormal nerve conduction studies were obtained in five subjects, with three having prolonged sensory distal latency, one having prolonged motor distal latency and one having both prolonged motor and sensory distal latencies with a low normal SNAP amplitude. Over half of the mercury levels were significantly higher in this abnormal group. The highest correlation obtained was between sensory latency and the number of months urine mercury exceeded 0.50 milligrams/liter. The authors conclude that exposure to elemental mercury can affect both motor and sensory peripheral nerve conduction and that the degree of involvement can be related to time integrated urine mercury levels.
Keywords
NIOSH-Grant; Nervous-system-function; Neuropathology; Mercury-compounds; Mercury-poisoning; Peripheral-nervous-system; Heavy-metals
Contact
Industrial & Operations Engr University of Michigan Industrial & Operations Engr Ann Arbor, Mich 48109
CAS No.
7439-97-6
Publication Date
19820101
Document Type
Final Grant Report
Funding Amount
282722
Funding Type
Grant
Fiscal Year
1982
NTIS Accession No.
PB88-247606
NTIS Price
A03
Identifying No.
Grant-Number-R01-OH-00707
NIOSH Division
OEP
Source Name
University of Michigan Medical Center, Department of Physical Medicine and Rehabilitation, Ann Arbor, Michigan
State
MI
Performing Organization
University of Michigan at Ann Arbor
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