Mortality of chrome leather tannery workers and chemical exposures in tanneries.
Stern-FB; Beaumont-JJ; Halperin-WE; Murthy-LI; Hills-BW; Fajen-JM
NIOSH 1988 Jan; :149-181
A population of 9365 individuals was placed into a retrospective mortality analysis to determine the causes of death among chrome leather tannery workers who were working at one of two tanneries as of 1940. More than half of the workers had at least 22 years of work in this field in their employment history. Excesses of deaths caused by cirrhosis of the liver, suicide, and alcoholism were noted at one tannery and an excess in the number of accidental deaths at the other. However, in neither location did these appear to be occupationally related. Cancer deaths were in general lower than expected based on general population data, including lung cancer. Deaths from other respiratory system disorders were also lower than anticipated. The potential hazards to which workers in this industry were probably exposed included nitrosamines, chromate pigments, benzidine based direct dyestuffs, formaldehyde (50000), leather dust and aromatic organic solvents. At one tannery, an excess of kidney cancer was noted. At this location workers had suffered from exposure to dimethylamine-sulfate (23307053) which had been used to accelerate the dehairing process. An increased risk for liver cancer was also noted in an adjacent tanyard area.
Mortality-rates; Mortality-surveys; Carcinogenesis; Cancer-rates; Risk-analysis; Tanning-industry; Epidemiology; Leather-finishing; Leather-industry; Leather-workers
Proceedings of the Fourth NCI/EPA/NIOSH Collaborative Workshop: Progress on Joint Environmental and Occupational Cancer Studies, April 22-23, 1986, Rockville, Maryland, NIH Publication No. 88-2960