Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Microbial containment in conventional fermentation processes.

Authors
Martinez-KF; Sheehy-JW; Jones-JH; Cusick-LB
Source
Appl Ind Hyg 1988 Jun; 3(6):177-181
NIOSHTIC No.
00178520
Abstract
Engineering controls in conventional enzyme fermentation operations were evaluated to identify effective controls applicable to processes involving microorganisms. Walk through surveys were conducted at six fermentation facilities, with in/depth surveys conducted at three of the sites. The various control measures were evaluated by collecting environmental air samples for the microorganisms involved in the manufacturing processes. Bioaerosol samples were collected from potential emission sites (laboratory, seed tank, fermentor tank) using a cascade impactor; factory production strain was identified using a standardized microbiological test method combined with a sugar utilization profile. Degree of microbial containment was assessed by comparing sample concentrations around unit processes to background. Results indicated that controls were most needed around high energy operations (filtering operations, agitator shafts, sampling ports) where aerosolization was likely to occur; operator work practices contributed to the degree of microbial exposure during certain operations. The authors conclude that an effective microbial containment strategy should emphasize containment within a sealed system through engineering and appropriate work practices; monitoring and the use of personal protective equipment is also advised.
Keywords
NIOSH-Author; Workplace-studies; Air-quality-control; Microbiology; Control-methods; Work-practices; Air-contamination; Employee-exposure
CODEN
AIHYEX
Publication Date
19880601
Document Type
Journal Article
Fiscal Year
1988
NTIS Accession No.
NTIS Price
Issue of Publication
6
ISSN
0882-8032
NIOSH Division
DPSE
Source Name
Applied Industrial Hygiene
State
OH; GA
TOP