Parental Occupation and the Occurrence of Brain Tumors in Children.
Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, 1987:153 pages
A case/control study was conducted on brain tumors in children and parental occupation. Cases were children identified from tumor registries and diagnosed with a brain tumor from 1977 through 1981; for each case, three comparison children were randomly selected and matched to the case by age, sex, mother's racial/ethnic classification, and telephone prefix or neighborhood. Altogether, 361 cases and 1083 comparisons were selected. For each parent, all jobs held for at least 6 months were identified and coded by industry. Histological slides of the brain tumors were read, and tumors were classified on this basis. Results indicated that, in children, some maternal and paternal occupational exposures increased the risk of brain tumors, and that the increased risks were specific for brain tumors of certain types and locations. Using a computerized system which linked occupations and specific exposures to chemical and physical exposure categories, some positive associations were found between brain tumors and exposure of one or both parents. Organic compounds and ionizing radiation were the two agents for which the associations were strongest.
NIOSH-Contract; Contract-85-35509; Epidemiology; Central-nervous-system-disorders; Brain-tumors; Families; Transplacental-exposure; Occupational-exposure; Radiation-exposure;
Final Report, Order No. 85-35509, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, 153 pages, 38 references