Updated information on health hazards associated with lead-chromate (7758976) (chrome pigment) was discussed. Results of an epidemiologic study and an industrial hygiene survey of three lead- chromate facilities sponsored by the Dry Color Manufacturer's Association (DCMA) were summarized. The epidemiologic study, with a cohort of 548 men, showed that workers exposed to lead-chromate at two facilities had a three fold excess of respiratory cancer. Employees at the third facility, who had zinc-chromate (13530659) exposure as well as lead-chromate exposure, also had a significant excess of mortality due to respiratory cancer. Additionally, a seven fold excess in stomach cancer mortality was observed in employees at the third facility. The industrial hygiene survey showed that nearly half of the samples at the three facilities reached or exceeded the OSHA standards for lead (7439921) and chromium (7440473). The current standards at the time of this report were as follows: lead, 0.2mg/m3; chromium as soluble chromium or chromium salts, 0.5mg/m3, and chromium as chromic-acid (7738945) or chromates, 0.1mg/m3. It is concluded that the results of the DCMA epidemiologic and industrial hygiene studies indicate that lead- chromate should be regarded as a human carcinogen.