Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

A case-control study of skin cancer in the tire and rubber manufacturing industry.

Authors
Bourguet-CC; Checkoway-H; Hulka-BS
Source
Am J Ind Med 1987 Apr; 11(4):461-473
NIOSHTIC No.
00169143
Abstract
A case/control study of skin cancer in the tire and rubber manufacturing industry was conducted. The cohort consisted of 65 white male rubber workers with histologically confirmed squamous cell carcinoma of the skin. They were matched to 254 white male rubber workers without skin cancer with respect to company, year of birth, and year of hire. Industry jobs were classified into 100 occupational titles; subjects were matched by occupational title. Each occupational title was rated for skin contact with rubber stock, carbon-black (1333864), lubricating and extender oils, and solvents. The relative risk of skin cancer associated with different degrees of exposure was estimated by the odds ratio. The relative risk of skin cancer increased with increasing degrees and duration of exposure to rubber stock and lubricating oil; however, the increases were not significant. Analyses of subgroups showed that these trends were strongest in workers born after 1900 and in those whose skin cancer was diagnosed before the age of 70. No evidence of an association of skin cancer with the other agents was seen. The authors conclude that rubber stock and lubricating oils are associated with an increased risk of skin cancer in the rubber manufacturing industry. They note that the study materials have not been analyzed. They assume that they are contaminated with polycyclic aromatic hydrocarbons (PAHs) and that PAHs are the actual carcinogens.
Keywords
NIOSH-Publication; NIOSH-Grant; Epidemiology; Case-studies; Skin-cancer; Rubber-manufacturing-industry; Rubber-workers; Risk-factors; Risk-analysis; Polycyclic-aromatic-hydrocarbons; Author Keywords: polycyclic hydrocarbons; occupation; epidemiology
CODEN
AJIMD8
CAS No.
1333-86-4
Publication Date
19870401
Document Type
Journal Article
Funding Amount
92236
Funding Type
Grant
Fiscal Year
1987
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-01023
Issue of Publication
4
ISSN
0271-3586
Source Name
American Journal of Industrial Medicine
State
NC
Performing Organization
Epidemiology University of North Carolina Occupational Hlth Studies Grp Chapel Hill, NC 27514
TOP