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Theories of electrostatic lung deposition of inhaled aerosols.

Authors
Yu-CP
Source
Ann Occup Hyg 1985 Apr; 29(2):219-227
NIOSHTIC No.
00168541
Abstract
The fundamental physics of charged particle deposition are reviewed. Also developed is a computational model to predict the amount and site of deposition in the human respiratory tract under various conditions. Particle charge can lead to a significant increase in aerosol deposition in the lung. At low concentrations, for environmental aerosols, the deposition increase primarily results from the presence of the image force acting on the particle, and the sign of charge does not affect deposition. In most cases, particle charge level is moderate and therefore conventional mechanisms control the amount of deposition. A charge level thus exists for each particle size below which the effect of particle charge on deposition is not significant. The values of this charge level are calculated for particles in the size range where deposition is dominated by sedimentation. As derived, the theory presented applies only to spherical, compact, or isometric particles. For fibrous particles carrying a charge, interaction between the particle and the airway wall may affect the particle and its deposition. Impaction, sedimentation, and interception depositions of these particles are thus different due to changes in torque and force on the particle.
Keywords
NIOSH-Publication; NIOSH-Grant; Inhalants; Respiratory-irritants; Particulate-dust; Lung-irritants; Particulate-sampling-methods; Aerosol-particles; Aerosol-sampling
CODEN
AOHYA3
Publication Date
19850401
Document Type
Journal Article
Funding Amount
215528
Funding Type
Grant
Fiscal Year
1985
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-00923
Issue of Publication
2
ISSN
0003-4878
Source Name
Annals of Occupational Hygiene
State
NY
Performing Organization
State University of New York at Buffalo, Buffalo, New York
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