Workers perceptions of exposure to job related harmful substances, working conditions and risk of injury were analyzed according to occupation, age, race and sex, using data obtained from the Health Promotion and Disease Prevention Questionnaire used in the 1985 National Health Interview Survey. More men than women were aware of risk from exposure to harmful substances, working conditions and risk of injuries. Forty four percent of the workers perceived exposure to chemicals, the greatest proportion being represented by women in the 18 to 29 year age group. More than 70 percent of men employed as sawing machine operators, brickmasons, stonemasons, bus drivers, operating engineers and automobile body repairers believed that they could develop respiratory diseases because of their exposure to harmful substances. Among women, 83 percent of textile sewing machine operators and 57 percent of hairdressers and cosmetologists expressed the same belief. Noise, the most frequently mentioned health endangering work related condition was reported by greater proportions of men than women for all age groups. Mental stress was mentioned more often by women than by men. Perceived risk of injuries was high for injuries from vehicles, machinery and tools, and falls. Men whose occupation involved the driving of vehicles and sales representatives in mining, manufacturing or wholesale, had perceived risks of injuries from vehicles ranging from 70 to 89 percent. Female bus drivers had a 94 percent perceived risk of injuries.