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Reproductive effects of occupational exposures.

Authors
Pries-CN
Source
Am Fam Phys 1981 Aug; 24(2):161-165
NIOSHTIC No.
00157043
Abstract
Effects of occupational exposure to toxic materials on human reproductive capacity are reviewed. Employment trends and legal requirements in the treatment of pregnant workers are described. The need for a periodic reappraisal of hazards both inside and outside the workplace is emphasized. The six stages in which the human reproductive system is susceptible to environmental factors are identified. In stage 1, the production of release of sufficient viable sperm or ova may be affected. Stage 2 is characterized by mutations or chromosomal damage to the ova or sperm before fertilization. Exposure to vinyl-chloride (75014) may cause this type of effect. Environmental factors such as toxic secretions in the male reproductive tract may interfere with fertilization in stage 3. In stage 4, implementation of the ovum may be prevented by the local chemical environment. This effect may explain reduced fertility due to trichloroethylene (79016) exposure. Stage 5 is characterized by impaired growth and development of the embryo due to maternal/fetoplacental toxic effects such as those due to organic mercury (7439976) compounds. In stage 6, offspring can be affected after birth by the presence of toxins in breast milk. Toxins known to affect human reproduction and their effects are listed. The author concludes that increased efforts to evaluate workplace hazards to human reproduction are resulting in a better environment.
Keywords
NIOSH-Grant; Occupational-hazards; Toxic-effects; Industrial-exposures; Reproductive-hazards; Chromosome-disorders; Workplace-studies; Biological-factors; Genetic-factors; Reproductive-system; Health-hazards
Contact
Environmental Health University of Minnesota 1158 Mayo Memorial Minneapolis, Minn 55455
CODEN
AFPYAE
CAS No.
75-01-4; 79-01-6; 7439-97-6
Publication Date
19810801
Document Type
Journal Article
Funding Amount
7317174
Funding Type
Grant
Fiscal Year
1981
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-T15-OH-007098; Grant-Number-T42-OH-007098
Issue of Publication
2
ISSN
0002-838X
Priority Area
Training
Source Name
American Family Physician
State
MN
Performing Organization
University of Minnesota of Mnpls-St Paul, Minneapolis, Minnesota
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