Development of a sampling and analytical method for styrene oxide, November 1, 1978-March 31, 1979.
Stampfer-JF; Hermes-RE; Weeks-RW Jr.; Campbell-EE; Ettinger-HJ
NIOSH 1979 Dec; :1-14
A method was developed for collecting and analyzing airborne styrene- oxide (96093). Test atmospheres of styrene-oxide were generated by injection of the compound into a flowing airstream in which the relative humidity was either 80 percent or less than 10 percent. The concentration of styrene-oxide ranged from 0.14 to 2.40 micrograms (microg) per liter. The test atmosphere was sampled into a three stage sampler consisting of a glass fiber filter, a 50 milligram (mg) primary bed, and a 25mg backup sorbent bed of 35/60 mesh Tenax GC. After sampling, the styrene-oxide was desorbed from the Tenax GC with ethyl-acetate, and an aliquot of the desorbing solvent was analyzed by gas liquid chromatography. A 1.2 meter, silanized glass column with carbowax 1540 on 60/80 chromosorb was used with a flame ionization detector. Tenax GC had the best combination of capacity and recovery of styrene-oxide of all the sorbents tested. Greater than 6mg of styrene-oxide were adsorbed to the bed and recoveries of 97.7 percent and 94 percent were found after 28 days of storage at 2 degrees-C and 14 days at 22 degrees, respectively. Relative humidity had no effect on the average recovery of styrene-oxide. Several related compounds, including styrene-glycol (93561), did not interfere in the assay. Using the combined sampling and analysis technique, recoveries of greater than 95 percent were obtained over the range 0.5 to 44microg per sample. Minimum quantitation was less than 0.5microg per sample for the combined sampling and analytical method. The minimum concentration of quantitation for the analytical method was 0.5 nanogram (ng) per microliter, and the minimum concentration of detection was monitoring worker exposure to styrene-oxide in a variety of occupational environments.
Research; Quantitative-analysis; Air-quality-monitoring; Aerosol-particles; Airborne-particles; Air-sampling-equipment; Exposure-levels; Employee-exposure; Work-environment
NIOSH, Cincinnati, Ohio, Report No. LA-7979-PR, Interagency Agreement IA-78-11, 14 pages, 19 references