The incidence and progression of pneumoconiosis over nine years In U.S. coal miners: II. Relationship with dust exposure and other potential causative factors.
Attfield-M; Reger-R; Glenn-R
Am J Ind Med 1984 Nov; 6(6):417-425
Progression of pneumoconiosis over 9 years in US coal miners and its relationship to causative factors such as dust exposure and composition were examined. The study began in 1970 and consisted of over 9000 miners. At the end of the study, 1470 miners remained in the cohort. X-rays were analyzed by the side by side method. Occupational history of individual miners and dust samples were collected. The correlations between dust concentration and X-ray changes over the 9 years were examined. Reported dust exposures were low and generally under the current 2 milligrams per cubic meter (mg/m3) standard. No link between dust concentration and disease progression could be detected. There was some evidence that radiological change was related to dust exposures prior to the study in both coal and non coal mines, thus occurring before the current dust standards were mandated. Neither migration of miners nor mining method appeared to be associated with disease incidence or progression. The incidence of pneumoconiosis over the 9 year period was consistent with the predicted incidence from established dose response curves interpolated at dust concentrations applicable to US dust standards. The authors conclude that increased periods of study as well as increased miner participation are necessary in order to obtain more information on the incidence and progression of pneumoconiosis in coal miners under the current dust standard.
NIOSH-Author; Medical-research; Epidemiology; Disease-incidence; Occupational-respiratory-disease; Quantitative-analysis; Radiographic-analysis; Industrial-dusts; Airborne-particles; Exposure-levels; Risk-analysis; Employee-exposure
American Journal of Industrial Medicine