Review, Summarization, And Evaluation Of Literature To Support The Update And Revision Of Criteria Documents. XII. Mercury.
NIOSH 1977 Apr:57 pages
An occupational hazard assessment of inorganic mercury (7439976) (Hg) is reviewed and evaluated. The review is intended to provide an update of existing NIOSH criteria documents. A number of investigations explore methods of concentrating, isolating, and storing aqueous and biological samples. Atomic absorption and fluorescence spectroscopy remain the preferred methods for Hg analysis. The use of solid adsorbents for air sampling is potentially a superior method to collection by impingement in a solvent. Biological Hg may be extracted by using a glass fiber disc coated with dithiocarbamate or extracted as the dithizone complex into chloroform. Hg has been removed from food by electrochemical deposition or neutron activation analysis. Humans may be exposed to Hg via inhalation of vapors and dust or skin or gastrointestinal tract absorption. Exposure to Hg may not be limited to the workplace if contaminated clothing is not removed and hands of workers are not carefully washed. In addition to measuring urine as an indicator, researchers have also used sensitive tremor, psychomotor, and electromyographic tests to evaluate subclinical exposure. Toxic amounts of Hg produce renal, genetic, and biochemical effects. The authors suggest the need to characterize the enzyme and inhibiting effects of Hg on tissue, examine the interaction of Hg with cell membranes of the renal tubules, develop epidemiologic investigations of working populations, and to pursue the effects of Hg exposure on reproduction.
NIOSH-Contract; Employee-exposure; Occupational-exposure; Poisons; Metal-poisoning; Aqueous-solutions; Analytical-methods; Chemical-analysis; Contract-210-76-0167;
NIOSH, U.S. Department of Health, Education, and Welfare, Rockville, Maryland