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Behavioral and neurological effects of mercury. Terminal progress report.

Authors
Langolf-GD
Source
University of Michigan, Ann Arbor, Michigan, 1981 Jan; :1-7
Link
NIOSHTIC No.
00134969
Abstract
Epidemiological studies of the behavioral and neurological effects of mercury (7439976) (Hg) were conducted. A total of 147 workers in chloralkali factories were administered a memory scanning test at selected intervals. Monthly urine specimens were analyzed for Hg over a 12 month period. The 12 month average urinary Hg concentration was 0.0 to 0.41 milligrams per liter (mg/l). A statistically significant trend toward slowed memory scanning was correlated with increasing Hg exposure. The data was treated by regression analysis and showed an increase in memory scanning time of 4.9 milliseconds per item for each 0.1mg/l increase in urinary Hg. Sixty workers were administered the 50 percent threshold test and their urinary Hg concentrations were determined monthly for 12 months. The 12 month average of urinary Hg was 0 to 0.258mg/l. A significant reduction in the 50 percent threshold span occurred which was correlated with urinary Hg concentrations. Some 138 workers who had average urinary Hg concentrations of 0.15mg/l were given neurological and nerve conduction examinations. Mild sensory neuropathy was observed in most of these workers. The author notes that effects on short term memory function could occur at concentrations below 0.25mg/l Hg.
Keywords
NIOSH-Grant; Heavy-metal-poisoning; Biological-effects; Medical-surveys; Dose-response; Industrial-medicine; Employee-exposure; Health-hazards; Occupational-medicine
CAS No.
7439-97-6
Publication Date
19810101
Document Type
Final Grant Report
Funding Amount
282722
Funding Type
Grant
Fiscal Year
1981
NTIS Accession No.
PB84-241611
NTIS Price
A02
Identifying No.
Grant-Number-R01-OH-00707
NIOSH Division
OEP
Source Name
University of Michigan, Ann Arbor Michigan
State
MI
Performing Organization
University of Michigan at Ann Arbor
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