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Walk-Through Survey Report No. CT-116-18a: Control Technology For Fermentation Processes At Wyeth Laboratories, Inc., West Chester, Pennsylvania.

Authors
Martinez-KF
Source
NIOSH 1985 Oct:10 pages
Link
NIOSHTIC No.
00131544
Abstract
A walk through survey was conducted at Wyeth Laboratories, Incorporated (SIC-2833), West Chester, Pennsylvania in November, 1983. The purpose of the survey was to evaluate the control technology for the fermentation processes. The facility produced penicillin-V (87081) and penicillin-G (61336) using the microbial strain Penicillium-chrysogenum. Engineering controls consisted primarily of enclosing the production process and growth and holding tanks, and transferring batch broth mixtures or concentrated liquid penicillin through a sterilized pipe network. Employee contact with the production processes was minimal except for equipment maintenance or manual broth sample extraction. Most of the large scale process operations were controlled by a central computer system. The company had a pre employment training program to orient new employees with process equipment use, operation, and safety procedures. Medical examinations were available for fermentation and extraction process workers. Safety shoes and glasses and disposable dust respirators were provided. The author concludes that Wyeth has in operation an apparently effective system of control measures.
Keywords
NIOSH-Author; NIOSH-Survey; Control-technology; Field-Study; Laboratories; Workers; Exposure-limits; Industrial-hygiene; Safety-engineering; Health-engineering; Analytical-models; Safety-equipment; CT-116-18a; Region-3;
CAS No.
87-08-1; 61-33-6;
Publication Date
19851001
Document Type
Field Studies; Control Technology
Fiscal Year
1986
NTIS Accession No.
PB86-145166
NTIS Price
A02
Identifying No.
CT-116-18a
NIOSH Division
DPSE;
Priority Area
Control Technology and Personal Protective Equipment; Research Tools and Approaches; Control-technology;
SIC Code
2833;
Source Name
Division of Physical Sciences and Engineering, NIOSH, U.S. Department of Health and Human Services, Cincinnati, Ohio, Report No. CT-116-18a, 10 pages
State
PA; OH;
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