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HHE report: HETA-80-79-1189, Rexall Drug Company, St. Louis, Missouri.

Authors
Watanabe-AS; Ruhe-RL; Hervin-RL
Source
NIOSH 1982 Sep; :1-25
NIOSHTIC No.
00129627
Abstract
Chemical exposures at the Rexall drug manufacturing facility (SIC- 2834), St. Louis, Missouri were investigated. The study was requested by the Oil, Chemical, and Atomic Workers International Union because of employee reports of nosebleeds, discolored urine, chest tightness, and breathing difficulties. The survey was performed in February, April, and July 1981. Environmental and medical evaluations were conducted. Total particulate concentrations in personal breathing zones ranged from 0.4 to 32.5 milligrams per cubic meter (mg/m3) compared to an American Conference of Governmental Industrial Hygienists threshold limit value (TLV) of 5.0mg/m3. Ferrous-sulfate (10028225) concentration peaked at 7.83mg/m3 (TLV: 1mg/m3). Methylene-chloride (75092) concentrations peaked at 361mg/m3 (NIOSH criteria: 261mg/m3). Isopropyl-alcohol (67630) concentrations peaked at 1180mg/m3 (NIOSH criteria: 984mg/m3). Five of seven ferrous-sulfate workers reported cough, nose, throat, or skin irritation, or headache. All four employees who worked with ferrous-sulfate on 2 consecutive days had increases both in serum iron concentrations and percent saturation of iron binding capacity. Eleven of 13 niacin workers reported skin symptoms. The authors conclude that a health hazard did exist due to high exposure to total dust, ferrous-sulfate, isopropyl-alcohol, and methylene-chloride. The authors recommend a respirator program and engineering controls.
Keywords
NIOSH-Author; NIOSH-Health-Hazard-Evaluation; Hazards-Confirmed; Pharmaceutical-industry; Environmental-health-monitoring; Medical-monitoring; Respiratory-protective-equipment; Dust-exposure; Region-7; HETA-80-79-1189; NIOSH-Technical-Assistance-Report
CAS No.
10028-22-5; 75-09-2; 67-63-0
Publication Date
19820901
Document Type
Hazard Evaluation and Technical Assistance; Field Studies
Fiscal Year
1982
NTIS Accession No.
PB84-151612
NTIS Price
A03
Identifying No.
HETA-80-79-1189
NIOSH Division
DSHEFS
SIC Code
2834
Source Name
Hazard Evaluations and Technical Assistance Branch, NIOSH, Cincinnati, Ohio, 25 pages, 12 references
State
MO; OH
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