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Investigation of an apparent increased prevalence of brain tumors in a U.S. petrochemical plant.

Authors
Alexander-V; Leffingwell-SS; Lloyd-JW; Waxweiler-RJ; Miller-RL
Source
Ann NY Acad Sci 1982 Apr; 381(1):97-107
NIOSHTIC No.
00126034
Abstract
An apparent increased prevalence of brain tumor deaths in a petrochemical facility in Texas was investigated. These studies were a part of more complete occupational health evaluation undertaken by OSHA, NIOSH and the company. Twenty cases of primary brain cancer death were examined using work history data. The interval from first employment to death varied from 3.5 to 36 years, with a median of 24 years. All cases occurred in males; 80 percent of the tumors were glioblastomas. Preliminary examination of work histories failed to establish any common job title, department code or chemical exposure. Mortality studies revealed an excess brain cancer risk among rubber (SIC-3069), pharmaceutical (SIC-2834), vinyl-chloride (75014) (SIC-2821), chemists (SIC-8071), and petrochemical and oil refinery workers (SIC-2911). An elevated risk was observed among veterinarians (SIC-0742), machinists (SIC-3599), lead smelter (SIC-3332) and aluminum reduction (SIC-3334) workers. No specific causative agents were clearly identified, with the exception of vinyl-chloride. The authors conclude that these tumors are the likely result of occupational chemical exposures.
Keywords
NIOSH-Author; Health-surveys; Epidemiology; Industrial-hygiene; Industrial-chemicals; Medical-research; Cancer-rates; Mortality-rates
CODEN
ANYAA9
CAS No.
75-01-4
Publication Date
19820401
Document Type
Journal Article
Fiscal Year
1982
NTIS Accession No.
NTIS Price
ISBN No.
9780897661522
Issue of Publication
1
ISSN
0077-8923
SIC Code
3069; 2834; 2821; 8071; 2911; 3599; 3332; 3334
Source Name
Annals of the New York Academy of Sciences
State
TX; DC; OH
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