A comparative study of aerosol deposition in different lung models.
Am Ind Hyg Assoc J 1982 Jan; 43(1):54-65
Lung models for the study of aerosol deposition are compared. Various previously reported lung models were compared by sealing their original data to an initial lung volume of 3000 cubic centimeters. Airway diameters, number of airways, the cumulative volume versus airway generation, and the cross sectional area versus the distance from the trachea were compared and a mathematical model examined deposition patterns. Total deposition did not vary appreciably from model to model while large differences existed in regional deposition. Deposition profiles along the airways from different models also showed different patterns. The authors state that the differences in deposition from various lung models may be explained by differences in airway dimensions and the number of structures in the various models possibly reflecting intersubject variability in human lung morphology.
NIOSH-Publication; NIOSH-Grant; Pulmonary-system; Dispersion; Body-distribution; Pulmonary-function; Aerosol-particles; Simulation-methods; Mathematical-models
Engineering Science S U N Y - at Buffalo Dept of Engineering Science Buffalo, N Y 14214
American Industrial Hygiene Association Journal
State University of New York at Buffalo, Buffalo, New York