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Power considerations in epidemiologic studies of vinyl chloride workers.

Authors
Beaumont-JJ; Breslow-NE
Source
Am J Epidemiol 1981; 114(5):725-734
NIOSHTIC No.
00121087
Abstract
Nine retrospective mortality studies of vinyl-chloride (75014) workers were statistically evaluated. The statistical powers of mortality studies were calculated with respect to the liver, brain, and lung sites and plotted on power curves to relate positive and negative findings to power, and to show the variability in powers. The results of the liver and brain cancer studies were consistent with an etiologic role for vinyl-chloride. In the case of lung cancer, two studies with very high power or excess risk yielded negative results indicating that vinyl-chloride was not a lung carcinogen. The authors conclude that power considerations are a useful epidemiologic tool.
Keywords
Plastics; Chemical-manufacturing-industry; Chemical-industry-workers; Epidemiology; Health-surveys; Mortality-rates
CODEN
AJEPAS
CAS No.
75-01-4
Publication Date
19810101
Document Type
Journal Article
Fiscal Year
1981
NTIS Accession No.
NTIS Price
Issue of Publication
5
ISSN
0002-9262
Source Name
American Journal of Epidemiology
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