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Health hazard alert: benzidine-, o-tolidine, and o-dianisidine- based dyes.

Authors
NIOSH
Source
NIOSH 1980 Dec; :1-36
NIOSHTIC No.
00118761
Abstract
Studies on the carcinogenicity and metabolism of benzidine (92875), o-tolidine (119937), and o-dianisidine (119904) based dyes are reviewed. Results of animal and human experiments are summarized. The authors conclude that exposure of workers to benzidine based dyes should be discontinued or reduced to the lowest possible concentrations. Exposure to o-tolidine and o-dianisidine based dyes should be limited. Recommendations to reduce worker exposure to these dyes include substituting less toxic dyes, establishing engineering controls for these chemicals, ensuring good housekeeping procedures and industrial hygiene practices, establishing restricted areas, informing employees of the adverse health effects of working with these dyes, placing employees with occupational exposure to these dyes under a medical monitoring program, providing facilities to remove residual chemicals, and monitoring employee exposures.
Keywords
NIOSH-Author; Aromatic-hydrocarbons; Dyes; Animal-studies; Humans; Medical-research; Worker-health; Safety-engineering
CAS No.
92-87-5; 119-93-7; 119-90-4
Publication Date
19801201
Document Type
Numbered Publication; Alert
Fiscal Year
1981
NTIS Accession No.
PB87-148219
NTIS Price
A04
Identifying No.
(NIOSH) 81-106
Source Name
National Institute for Occupational Safety and Health
State
OH
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