Skip directly to search Skip directly to A to Z list Skip directly to page options Skip directly to site content

NIOSHTIC-2 Publications Search

Search Results

Exposure to mixtures of airborne contaminants. Final progress report grant R01-OH-00472.

Authors
Smith-FA
Source
University of Rochester School of Medicine and Dentistry, Rochester, NY 1977 Apr; :1-25
Link
NIOSHTIC No.
00112242
Abstract
The effect of particulate and gaseous airborne pollutants was studied in Camm-Harty-guinea-pigs. Animals were exposed for 6 hours per day, 5 days per week for 16 weeks to 1.2 milligrams per cubic meter (mg/cu m) of fluorspar (7789755) dust of respirable size, or to 3.3mg/cu m of hydrogen-fluoride (7664393) (HF). The animals were maintained for up to 89 days after exposure. Both agents caused increases in the fluoride burden in the plasma, femur and feces. Exposure to HF also increased the number of free alveolar macrophages, while the incidence of patchy pneumonitis decreased. Pulmonary edema persisted for 2 days after exposure. All responses returned to normal after exposure was terminated and no further adverse effects were seen. The author recommends that fluoride containing pollutants in the workplace be characterized and that epidemiological studies be performed for populations living near fluoride emitting industries.
Keywords
NIOSH-Grant; Biochemistry; Physiology; Laboratory-animals; Air-contamination; Pulmonary-system-disorders
Contact
Radiation Biology & Biophysics University of Rochester Dept of Rad Biol & Biophysics Rochester, N Y 14642
CAS No.
7789-75-5; 7664-39-3
Publication Date
19770430
Document Type
Final Grant Report
Funding Amount
107436
Funding Type
Grant
Fiscal Year
1977
NTIS Accession No.
NTIS Price
Identifying No.
Grant-Number-R01-OH-00472
NIOSH Division
OEP
Priority Area
Pulmonary-system-disorders
Source Name
University of Rochester School of Medicine and Dentistry, Rochester, NY
State
NY
Performing Organization
University of Rochester, Rochester, New York
TOP