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Methyl-N-Butyl Ketone and Peripheral Neuropathy.

Authors
Mallov-JS; Marceleno-T; Fontaine-R
Source
NIOSH 1975 Jun:23 pages
Link
NIOSHTIC No.
00107091
Abstract
The neurotoxicity of methyl-butyl-ketone (591786) (MBK) is discussed. Animal toxicity studies and five case reports of peripheral neuropathy in exposed workers are reviewed. Results of neurologic examinations of 207 workers from four paint manufacturing companies (SIC-2851) are evaluated. The authors conclude that MBK can cause peripheral neuropathy in humans, even at concentrations as low as 100 parts per million. Proper engineering controls can reduce the hazards of exposure to MBK.
Keywords
NIOSH-Author; NIOSH-Survey; Field-Study; IWS-47-3; Region-5; Pesticides-and-agricultural-chemicals; Health-surveys; Workplace-studies; Air-contamination; Occupational-health-programs; Case-studies;
CAS No.
591-78-6;
Publication Date
19750601
Fiscal Year
1975
NTIS Accession No.
PB81-229981
NTIS Price
A03
Identifying No.
IWS-47-3
NIOSH Division
DFSCI;
SIC Code
2851;
Source Name
NIOSH, Division of Field Studies and Clinical Investigations, U.S. Department of H.E.W, Cincinnati, Ohio, 23 pages, 13 references
State
OH;
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