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Chloroprene: Adverse Effects on Reproduction.

Authors
Infante-PF
Source
NIOSH 1980 Oct:87-101
Link
NIOSHTIC No.
00105771
Abstract
Studies on the reproductive effects of chloroprene (126998) are reviewed. Information is provided on the mutagenicity and carcinogenicity of the chemical reproductive studies in laboratory animals and epidemiological surveys of exposed worker populations are discussed together with the incidence of chloroprene induced chromosomal abnormalities. The author concludes that chloroprene is a potential human mutagen, and recommends several areas of future research such as evaluation of the dominant lethal test, the effects of chloroprene metabolites and the determination of the optimum level of significance for chromosomal aberration tests.
Keywords
Toxic-effects; Reproductive-effects; Butadienes; Carcinogens; Laboratory-animals; Occupational-exposure; Workers; Epidemiology; Chromosome-damage; Metabolites;
CAS No.
126-99-8;
Publication Date
19801001
Fiscal Year
1981
NTIS Accession No.
NTIS Price
NIOSH Division
DSHEFS;
Source Name
Proceedings of a Workshop on Methodology for Assessing Reproductive Hazards in the Workplace, April 19-22, 1978, P.F. Infante and M.S. Legator, Eds. Division of Surveillance, Hazard Evaluations and Field Studies, NIOSH, U.S. Department of Health and Human Services
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